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There are several matches for 'multidrug efflux transporter'.
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5703 matches
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organism
protein
1)
Mus musculus
Abcb1b - ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D- glucosylceramides and sphingomyelins. Energy-dependent
efflux
pump responsible for decreased drug accumulation in
multidrug
-resistant cells; Belongs to the ABC
transporter
superfamily. ABCB family.
Multidrug
resistance exporter (TC 3.A.1.201) subfamily.
[a.k.a. ENSMUSP00000143612, A0A0G2JF49, B2RUR3]
2)
Caenorhabditis elegans
pgp-1 -
Multidrug
resistance protein pgp-1; Energy-dependent
efflux
pump responsible for decreased drug accumulation in
multidrug
-resistant cells; Belongs to the ABC
transporter
superfamily. ABCB family.
Multidrug
resistance exporter (TC 3.A.1.201) subfamily.
[a.k.a. K08E7.9, P34712, NP_502413]
3)
Escherichia coli K12
mdtK -
Multidrug
efflux
system
transporter
;
Multidrug
efflux
pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP). Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium. Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing [...]
[a.k.a. AAT48136.1, b1663, YP_025307]
4)
Saccharomyces cerevisiae
PDR5 - Pleiotropic ABC
efflux
transporter
of multiple drugs; Plasma membrane ATP-binding cassette (ABC)
transporter
;
multidrug
transporter
actively regulated by Pdr1p; also involved in steroid
transport
, cation resistance, and cellular detoxification during exponential growth; PDR5 has a paralog, PDR15, that arose from the whole genome duplication.
[a.k.a. YOR153W, Suppressor of toxicity of sporidesmin, 854324]
5)
Escherichia coli K12
mdtE - Anaerobic
multidrug
efflux
transporter
, ArcA-regulated; Part of the tripartite
efflux
system MdtEF-TolC, which confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
[a.k.a. b3513, AAC76538.1, MDTE_ECOLI]
6)
Escherichia coli K12
mdtF - Anaerobic
multidrug
efflux
transporter
, ArcA-regulated; Part of the tripartite
efflux
system MdtEF-TolC, which confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
[a.k.a. AAC76539.1, b3514, 948030]
7)
Escherichia coli K12
mdtI -
Multidrug
efflux
system
transporter
; Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS; Belongs to the drug/metabolite
transporter
(DMT) superfamily. Small
multidrug
resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
[a.k.a. AAC74671.1, b1599, Spermidine export protein MdtI]
8)
Escherichia coli K12
mdtJ -
Multidrug
efflux
system
transporter
; Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS; Belongs to the drug/metabolite
transporter
(DMT) superfamily. Small
multidrug
resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
[a.k.a. b1600, AAC74672.1, ABE-0005345]
9)
Escherichia coli K12
hsrA - Putative
multidrug
or homocysteine
efflux
system; Putative
transport
protein (MFS family); high copy suppressor of RspA: relieves RspA-mediated reduction of sigma(S) levels; overexpression also reduces MetE activity; effect proposed to be via an elevation in levels of homocysteine, causing a concomitant increase in homocysteine thiolactone; overexpression has no effect on resistance to a variety of toxic compounds; overexpression has no effect on resistance to a variety of toxic compounds; Belongs to the major facilitator superfamily. EmrB family.
[a.k.a. b3754, AAC76777.1, P31474]
10)
Escherichia coli K12
emrE - DLP12 prophage;
Multidrug
transporter
that expels positively charged hydrophobic drugs across the inner membrane of E.coli., thereby conferring resistance to a wide range of toxic compounds. The drug
efflux
is coupled to an influx of protons. Is involved in the resistance of E.coli cells to methyl viologen, ethidium bromide and acriflavine. Is also able to
transport
tetraphenylphosphonium (TPP(+)) and benzalkonium. Belongs to the drug/metabolite
transporter
(DMT) superfamily. Small
multidrug
resistance (SMR) (TC 2.A.7.1) family.
[a.k.a. b0543, AAC73644.1, 3B61]
11)
Escherichia coli K12
sugE -
Multidrug
efflux
system protein; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Overexpression leads to resistance to a subset of toxic quaternary ammonium compounds such as cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations. Belongs to the drug/metabolite
transporter
(DMT) superfamily. Small
multidrug
resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
[a.k.a. AAC77108.2, b4148, AAC77108]
12)
Saccharomyces cerevisiae
STE6 - Alpha-factor-
transporting
ATPase; Plasma membrane ATP-binding cassette (ABC)
transporter
; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor
transport
; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates
multidrug
resistance in many chemotherapy-resistant tumors by
effluxing
toxic compounds from the cell.
[a.k.a. YKL209C, CAA33467.1, YKL209C_mRNA]
13)
Advenella kashmirensis WT001
AFK60743.1 - COG0841 Cation/multidrug efflux pump.
[a.k.a. TKWG_00045,
Multidrug efflux transporter
, I3U6V5_ADVKW,
multidrug efflux transporter
]
14)
Aeromonas salmonicida achromogenes
O23A_p4389 - Unannotated protein.
[a.k.a. GCA_000315855_00432,
Multidrug efflux transporter
, A0A1Z1NX98]
15)
Aeromonas salmonicida masoucida
GAJ49323.1 - Putative major facilitator superfamily transporter.
[a.k.a. ASA01S_045_00250, NZ_CP017143.1, O23A_p4389,
Multidrug efflux transporter
]
16)
Agrobacterium radiobacter
Arad_1360 -
Multidrug
efflux
transporter
.
[a.k.a. ACM25816.1,
Multidrug efflux transporter
, B9JBB0_AGRRK,
multidrug efflux transporter
]
17)
Agrobacterium radiobacter
Arad_3942 -
Multidrug
efflux
transporter
; Belongs to the major facilitator superfamily.
[a.k.a. ACM27773.1,
Multidrug efflux transporter
, ara:Arad_3942,
multidrug efflux transporter
]
18)
Anopheles sinensis
ZHAS_00013651 -
Multidrug
efflux
transporter
.
[a.k.a.
Multidrug efflux transporter
, A0A084W659_ANOSI, A0A084W659]
19)
Arthrobacter nitrophenolicus
ELT44791.1 -
Multidrug
efflux
transporter
; COG2076 Membrane
transporters
of cations and cationic drugs.
[a.k.a. G205_09628, ELT44791,
multidrug efflux transporter
,
Multidrug efflux transporter
]
20)
Azospirillum brasilense
AIB10768.1 - Major facilitator transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
[a.k.a. ABAZ39_01775,
Multidrug efflux transporter
, NZ_CP022253.1]
5703 matches
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